Application Aware Virtualization Backup

While participating in the GestaltIT Virtualization Field Day #2, I was asking Symantec about Application Aware Backups. In other words, could one backup an entire application, regardless of how the application was defined. This concept goes hand in hand with Application Aware Security measures. We can always backup VMs and their data to remote locations, but can we backup or maintain the application interactions within a multi-VM Application regardless of how it is defined.