Picking a Secure Hybrid Cloud Security Solution

In the past we have discussed the various aspects of the secure hybrid cloud, ranging from the data center through a transition stage and finally to and from the cloud. Unfortunately, picking just one security solution, or even one family of solutions, does not work, so we need to start thinking outside the box and pick the best based on our needs, which cover compliance as well as security. So how do we pick a security solution based on our needs?